Successful pregnancy by intracytoplasmic sperm injection after radiotherapy induced azoospermia

A 27 year old male, who underwent excision and radiotherapy for a pineal gland germinoma four years previously, subsequently developed panhypopituitarism and, thus, complete azoospermia. Gonadotrophin replacement therapy resulted in the production of a small number of motile spermatozoa which were used for Intracytoplasmic Sperm Injection (ICSI) into oocytes obtained from his wife. After successful fertilization and embryo transfer, a singleton intrauterine pregnancy was achieved which resulted in the normal delivery of a morphologically normal male live infant at term.(AU)

Initial experience with in-vitro fertilization technology in the English-speaking Caribbean

This audit documents the first experience with in-vitro fertilization techonlogy in the English-speaking Caribbean. From 1996 to 2000, 121 cycles have been performed in 99 couples utilizing these techniques. After ovarian stimulation, 1103 oocytes were retrieved (average 9.1) and of these, 65 percent fertilized normally, with embryo transfer possible in 111 cycles. Twenty-one pregnancies were recorded (21.2 percent per patient and 18.9 percent per embryo transfer) and the live birth rate per patient was 12.1 percent. The trend was for the success rate to be better in patients under age 36 years. (AU)